What's the difference between Extreme Ghostbusters and the Real Ghostbusters?

Well, seeing as the ghosts are tougher and more frightening than ever before, you need a new breed of Ghostbusters to take care of them…

What are those cool gizmos the crew use?

You have the PKE Meter, that detects spirit activity. Then you have your Ghost Trap, that pulls the ghoulies in and contains them. Add to that a Proton Gun for your common-or-garden spirit blasting, and voila! All your ghostbusting requirements are met!

If they're Ghostbusters why don't they bust Slimer, who's obviously a ghost?

Well, yeah, Slimer is a ghost but the most frightening thing about him is his appetite and table manners, not his ghostly presence!

How do they get from ghostbusting job to ghostbusting job?

Ah, the Ecto-1. Nifty, isn't it?